[smgj]

Da tror jeg du må forklare meg hva du legger i virkestoffer kontra amminosyrer. Alt vi spiser har jo en virkning. Noe har virkning i relativt små mengder i de fleste folk, andre stoffer krever større mengder. (Metanol kontra sukker f.eks...) Når det gjelder medisin kommer ikke nødvendigvis bivirkninger bare av virkestoffene, men kan også komme fra fillerne.

For enkelhets skyld kopierte jeg inn linkene som omhandler studier på migrene. Det er merkelig nok ingen som er utført på rotter.

Health Problem: Headache/Migraines

1. Year Published: 1985
   Full Reference: Aspartame: Possible Effect on Seizure Susceptibility. Wurtman, RJ. Lancet. Vol. 2, no. 8463, 1060 p. 1985
   Funded By: MIT
   Conclusion/Findings: Woman who drank large amounts of Diet Coke and other aspartame-flavored beverages experienced headaches, nausea, visual hallucinations, and a grand-mal seizure.
   Hyperlink to Study: http://md1.csa.com/partners/viewrecord.php?requester=gs&collection=ENV&recid=1 354938&q=Aspartame%3A+Possible+Effects+on+Seizure+ Suspectibility&
   uid=789675711&setcookie=yes
2. Year Published: 1987
   Full Reference: The Effect of Aspartame on Migraine Headache. Shirley M. Koehler, Alan Glaros. Headache: The Journal of Head and Face Pain. Vol 28, Issue 1, Nov. 12, 1987
   Funded By: Not known
   Conclusion/Findings: Ingestion of aspartame by migraine sufferers causes significant increases in headache frequency
   Hyperlink to Study: http://www3.interscience.wiley.com/j...49495/abstract
3. Year Published: 1998
   Full Reference: Aspartame as a Dietary Trigger of Headache. Richard B. Lipton, MD, Lawrence C. Newman, MD, Joel S. Cohen, MD, Seymour Solomon, MD. The Journal of Head and Face Pain. Vol. 29, Issue 2, pp. 90-92. Sept. 1998
   Funded By
   Conclusion/Findings: Finds that aspartame may be an important dietary trigger of headache in some people.
   Hyperlink to Study: http://www3.interscience.wiley.com/j...29393/abstract
4. Year Published: 1991
   Full Reference: Platelet Glycine, Glutamate and Aspartate in Primary Headache, D'Andrea, G., et al., 1991. Cephalalgia, Vol. 11, pp. 197-200.
   Funded By: Not known
   Conclusion/Findings: High levels of these amino acids were found in patients with migraine with aura compared to normal subjects and other headache groups
   Hyperlink to Study: http://cep.sagepub.com/content/11/4/197.abstract
5. Year Published: 1997
   Full Reference: Chewing Gum Headaches, Blumenthal, H.J., D.A. Vance, Headache, Volume 37, Number 10, pages 665-666. 1997
   Funded By: Department of Neurology, University of Oklahoma College of Medicine, Tulsa
   Conclusion/Findings: Chewing gum with aspartame provokes headaches
   Hyperlink to Study: http://www3.interscience.wiley.com/j...66706/abstract
6. Year Published: 2003
   Full Reference: The Diet Factor in Pediatric and Adolescent Migraine, Millichap JG, Yee MM. Pediatric Neurology, 2003 Jan;28(1):9-15
   Funded By: Not known
   Conclusion/Findings: Aspartame is one of the substances that trigger migraines in children and adolescents
   Hyperlink to Study: http://www.drcordas.com/education/Headaches/1doc.pdf
7. Year Published: 1994
   Full Reference: Aspartame Ingestion and Headaches: a Randomized Crossover Trial. S. K. Van Den Eeden, PhD, T. D. Koepsell, MD, MPH, W. T. Longstreth, Jr., MD, MPH, G. van Belle, PhD, J. R. Daling, PhD and B. McKnight, PhD, American Academy of Neurology, Neurology. 1994;44:1787
   Funded By: University of Washington
   Conclusion/Findings: This experiment provides evidence that, among individuals with self-reported headaches after ingestion of aspartame, a subset of this group report more headaches when tested under controlled conditions. It appears that some people are particularly susceptible to headaches caused by aspartame and may want to limit their consumption.
   Hyperlink to Study: http://www.neurology.org/cgi/content...e2=tf_ipsecsha
8. Year Published: 1990
   Full Reference: The Concept of Migraine as a State of Central Neuronal Hyperexcitability, KMA Welch, et all, 1990. Headache, Vol. 8, No. 4, pp 817-828.
   Funded By: Not known
   Conclusion/Findings: Finds that aspartate can cause migraine with aura associated with a state of central neuronal hyperexcitability
   Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/1979655
9. Year Published: 2001
   Full Reference: Migraine MLT-Down: An Unusual Presentation of Migraine in Patients with Aspartame-Triggered Headaches. Lawrence C. Newman, Richard B. Lipton, Headache: The Journal of Head and Face Pain, Vol. 41, Issue 9, pp. 899-901
   Funded By: The Headache Institute, St. Lukes-Roosevelt Hospital Center, New York
   Conclusion/Findings: Reports that aspartame may trigger headaches in susceptible individuals, and can worsen an ongoing attack of migraine.
   Hyperlink to Study: http://www3.interscience.wiley.com/j...97481/abstract
10. Year Published: 1988
    Full Reference: Aspartame as a Dietary Trigger of Headache, Richard B. Lipton, Lawrence C. Newman, Joel S. Cohen, Seymour Solomon, Headache: The Journal of Head and Face Pain, Vol. 29, Issue 2, pp. 90-92
    Funded By: Department of Neurology, Albert Einstein College of Medicine, Bronx, NY
    Conclusion/Findings: Reports that some patients with migraines reported aspartame as a trigger three times more often than those with other types of headache.
    Hyperlink to Study: http://www3.interscience.wiley.com/j...29393/abstract

Dette er altså studiene som omhandler migrene i artikkelen fra Dr. Mercola. Siden det ikke er han som har utført studiene så ser jeg ikke hvordan hans troverdighet, eller eventuelle mangel på sådan, er relevant.

Mitt poeng er at når folk sier at de får hodepine av lettbrus og saft inneholdende aspartam så ser jeg faktisk liten grunn til å mistro disse observasjonene. Så klart - de "kan" være feil... men også vitenskapsmenn har tatt feil - selv der hvor vitenskapelige undersøkelser legges til grunn. Ikke en gang, men flere ganger.

Jeg ser ingen grunn til å tro at studiene om aspartam har bedre kvalitet enn studiene om kolesterol. Ennå.

Men - jeg har ingen grunn til å påstå at det ikke er folk som kan spise/drikke aspartam UTEN å få problemer... jeg har bare svært vanskelig for å se at du kan bevise at folk IKKE kan få det av aspartam.